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Bioactive Heterocyles I

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  • Publisher: Springer
    Number Of Pages: 220
    Publication Date: 2006-09-14
    ISBN-10 / ASIN: 3540333509
    ISBN-13 / EAN: 9783540333500​
  • Binding: Hardcover​
Review

From the reviews:

"Bioactive Heterocycles I is a continuation of critical accounts about heterocyclic compounds within the series Topics in Heterocyclic Chemistry. The present volume provides comprehensive reviews of the chemistry and bioactivity of selected groups of heterocycles and natural products. Overall, this book covers in detail several classes of bioactive heterocyclic compounds including selected natural products. The focus is on the most recent advances, and the clarity of the presentation is very good. It should be of interest to individuals interested in the discovery and synthesis of bioactive small molecules, including research scientists in academia and industry. I would expect this book to be a standard reference in university and industrial libraries." (Gary Sulikowski, Journal of the American Chemical Society, Vol. 129 (15), 2007)

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Inorganic Biochemistry of Iron Metabolism: From Molecular Mechanisms to Clinical Consequences, 2nd Edition



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Hardcover: 358 pages
Publisher: John Wiley & Sons; 2 edition (October 15, 2001)
Language: English
ISBN: 047149223X


Product Description
Iron is of fundamental importance for the growth, development and well being of almost all living organisms. Multiple biological systems have been developed for the uptake, utilisation, storage and homeostasis of iron in microbes, plants and mammals. e.g. Both iron deficiency and iron overload are found extensively in man: the intimate links between iron and oxidative stress are associated with a wide range of pathologies; iron has a well established role in infections by a wide range of microorganisms and parasites; there is a close link between iron requirements and cellular division with implications for cancers and other metals such as copper and zinc are closely linked with iron metabolism.

The first edition of this book was published in 1991 and since then the extensive impact of molecular cell biology on the field of iron biochemistry has opened new horizons in our understanding of the transport and storage of iron and of its homeostasis. The explosive use of molecular biological techniques applied to cellular biology of iron metabolism has resulted in a rapid expansion in the literature that has led to the need for this second edition.

This collaboration between five specialist authors covers the fundamental concepts and applied aspects of iron biochemistry. Completely updated it reflects the latest advances in the field and now includes new chapters on iron and cell division and the interactions of iron with other metals.

Exploring the chemistry, biology, biochemistry, physiology and medical aspects of iron in biological systems from microorganisms to man this essential title:
* Introduces illustrations and colour photos to make the basic concepts far clearer
* Includes new chapters on iron and cell division and interactions of iron with other metals - particularly copper and zinc
* Provides additional anecdotes
* Incorporates an extensive and up-to-date bibliography
* Covers both fundamental and applied aspects


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Chemical Reagents for Protein Modification

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Product Details


  • Hardcover: 352 pages​
  • Publisher: CRC; 3 edition (November 15, 2004)​
  • Language: English​
  • ISBN-10: 0849319838​
  • ISBN-13: 978-0849319839​
  • Product Dimensions: 9.3 x 6.4 x 0.9 inches​
Product Description
Revised and updated, Chemical Reagents for Protein Modification, Third Edition is an encyclopedic work describing the many approaches to the site-specific modification of proteins. More than 2,000 references are cited describing the development of the various reagents. This book explores how the use of site-specific protein modification relates to a wide variety of biotechnology processes and products, such as protein microarrays, hydrogels, controlled-release pharmaceuticals, and biotherapeutics, and proteomics. With chapters focusing on analyses of individual amino acids, additional chapters cover chemical cross-linking and the chemical cleavage of peptide chains. There is considerable reference to the use of site-specific chemical modification in proteomics. The author pays particular attention to the general environmental factors that influence the reactivity of individual amino acid residues. He presents techniques for the characterization of modified proteins, including mass spectrometry, and includes increased coverage of spectroscopic techniques and crystallographic analyses. This is followed by coverage of nitrosylation reactions and other non-enzymatic modification processes. Specific reference is given to the differential labeling of protein functional groups with reagents labeled with stable isotopes. Resources include a list of current journals that publish site-specific chemical modification studies, the most commonly used reagents and their properties, and a contact list of reagent suppliers. Chemical Reagents for Protein Modification, 3rd Edition presents the most frequently used methods for the site-specific chemical modification of proteins, techniques for protein characterization, precise laboratory data for factors that influence reactivity and reproducibility, and industry-specific resources.


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Magnetic Cell Separation

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* Publisher: Elsevier Science
* Number Of Pages: 500
* Publication Date: 2007-11-08
* ISBN-10 / ASIN: 0444527540
* ISBN-13 / EAN: 9780444527547
* Binding: Hardcover


Book Description:

Cell separation is at the core of current methods in experimental biology and medicine. Its importance is illustrated by the large number of physical and biochemical principles that have been evaluated for application to cell separation. The development of cell separation methods is driven by the needs of biological and medical research, and the ever increasing demands for sensitivity, selectivity, yield, timeliness and economy of the process. The interdisciplinary nature of research in this area and the volume of information available in research publications and conferences necessitates a a basic description of the fundamental processes involved in magnetic cell separation that may help the user in navigating this wealth of information available online and in scientific publications. This book will appeal to researchers in many areas utilizing this technique including those working in cell biology, clinical research, inorganic chemistry, biochemistry, chemical engineering, materials science, physics and electrical engineering.

* Provides examples of how to calculate the volume magnetic susceptibility, a fundamental quantity for calculating the magnetic force acting on a cell, from various types of magnetic susceptibilities available in literature
* Introduces the elements of magnetostatics as they apply to cell magnetization and the magnetization of magnetic micro- and nano- particles used for cell separation
* Describes the parameters used to determine cell magnetophoresis

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Introduction to Biophysical Methods for Protein and Nucleic Acid Research

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Publisher: Academic Press
Number Of Pages: 510
Publication Date: 1995-11-06
Sales Rank: 2392759
ISBN / ASIN: 0122862309
EAN: 9780122862304
Binding: Hardcover
Manufacturer: Academic Press
Studio: Academic Press


Book Description:

The first of its kind, Introduction to Biophysical Methods for Protein and Nucleic Acid Research serves as a text for the experienced researcher and student requiring an introduction to the field. Each chapter presents a description of the physical basis of the method, the type of information that may be obtained with the method, how data should be analyzed and interpreted and, where appropriate, practical tips about procedures and equipment.

Key Features

* Modern Use of Mass Spectroscopy
* NMR Spectroscopy
* Molecular Modeling and Graphics
* Macintosh and DOS/Windows 3.x disks

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Biochemistry and Genetics: PreTest Self-Assessment and Review

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Publisher: McGraw-Hill Medical
Number Of Pages: 432
Publication Date: 2007-04-19 Sales Rank: 33703
ISBN / ASIN: 0071471839
EAN: 9780071471831
Binding: Paperback
Manufacturer: McGraw-Hill Medical
Studio: McGraw-Hill Medical


Book Description:

This one-of-a-kind test prep guide helps you to test your knowledge of essential biochemistry and genetics concepts for the USMLE Step 1; practice with 500 USMLE Step 1-style questions with referenced answers; review explanations for right and wrong answers; and build confidence, skills, and knowledge.


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Principles of Biochemistry With a Human Focus


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Product Details
  • Hardcover: 976 pages​
  • Publisher: Brooks Cole; 1 edition (May 14, 2001)​
  • Language: English​
  • ISBN-10: 0030973694​
  • ISBN-13: 978-0030973697​
  • Product Dimensions: 10.9 x 9.3 x 1.4 inches​
Product Description
PRINCIPLES OF BIOCHEMISTRY WITH A HUMAN FOCUS provides pre-med, junior, and senior science majors the most up-to-date coverage of biochemistry and a distinct focus on the topics most relevant to human health and medicine. Written by a chemist (Grisham) and a biologist (Garrett), the book presents biochemistry from a balanced perspective. PRINCIPLES OF BIOCHEMISTRY stresses the principles governing structure, function, and interactions of biological molecules.​

Book Info
Univ. of Virginia, Charlottesville. Textbook is provides the fundamental principles governing the structure, function, and interactions or biological molecules. Specifically discusses the molecular components of cells, protein dynamics, metabolism and its regulation, and information transfer. Features chapter exercises and summaries.​





The Biochemistry of Inorganic Polyphosphates​


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Product Details
  • Hardcover: 294 pages​
  • Publisher: Wiley; 2 edition (July 23, 2004)​
  • Language: English​
  • ISBN-10: 0470858109​
  • ISBN-13: 978-0470858103​
  • Product Dimensions: 9.9 x 6.7 x 0.8 inches​
Product Description​

Now in a second edition, Biochemistry of Inorganic Polyphosphates fills the need for an exhaustive resource on inorganic polyphosphate metabolism. The authors describe the structure and properties of these compounds and presents a comparative analysis of the newest and traditional methods of their extraction from cells. Distribution of polyphosphates in organisms, their localization in cells and tissues is also described.​

  • Comprehensive presentation of inorganic polyphosphate metabolism​
  • Follows polyphosphates in cells of organisms from different stages of evolution​
  • Presents methods for the analysis and study of polyP-dependent enzymes​
  • Comprehensive information on genetics, metabolism and biotechnology of polyphosphates​
  • Textbook and reference work on all aspects of polyphosphates​



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Biological Thermodynamics




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* Publisher: Cambridge University Press

* Number Of Pages: 396
* Publication Date: 2001-03-19
* Sales Rank: 2177504
* ISBN / ASIN: 0521791650
* EAN: 9780521791656
* Binding: Hardcover
* Manufacturer: Cambridge University Press

* Studio: Cambridge University Press



Book Description:




Biological Thermodynamics provides an introduction to the study of energy transformations for students of the biological sciences. Donald Haynie uses an informal writing style to introduce this core subject in a manner that will appeal to biology and biochemistry undergraduate students. The emphasis of the text is placed on understanding basic concepts and developing problem-solving skills throughout the text. The level of mathematical complexity is kept to a minimum. Each chapter provides numerous examples taken from different areas of biochemistry, as well as extensive exercises to aid understanding. Topics covered include energy and its transformation, the First Law of Thermodynamics, the Second Law of Thermodynamics, Gibbs Free Energy, statistical thermodynamics, binding equilibria and reaction kinetics, and a survey of the most exciting areas of biological thermodynamics today, particularly the origin of life on Earth.









Highlights in Bioorganic Chemistry: Methods and Applications




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Product Details


  • Paperback: 600 pages​
Publisher: Wiley-VCH; 1 edition (April 2, 2004)
Language: English
ISBN-10: 3527306560
ISBN-13: 978-3527306565
Product Dimensions: 9.4 x 6.7 x 1.2 inches​

Book Description​

This is a fascinating introduction to the topic. Spanning the spectrum of nucleic acid chemistry, carbohydrates, peptides, molecular recognition, biosynthesis and natural biosynthesis, right up to medical and biophysical chemistry, the book provides advanced students and those already working in the field with a balanced overview.​


In more than 30 contributions, a new generation of recognized scientists gives an account of the latest research in such areas as​
  • Artificial receptors for the stabilization of β-sheet structures​
  • Carbohydrate recognition by artificial receptors​
  • Combinatorial chemistry as a tool for the discovery of catalysts​
  • The interaction of NO and peroxynitrite with hemoglobin and myoglobin​
  • Inhibitors against human mast-cell-tryptase as a potential approach to conquering asthma​
  • The selectivity of DNA replication.
    A readily accessible survey for everyone wishing to stay abreast of developments​







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Theoretical Biochemistry

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Publisher: Elsevier Science
Number Of Pages: 718
Publication Date: 2001-01-01
Sales Rank: 1178855
ISBN / ASIN: 0444502920
EAN: 9780444502926
Binding: Hardcover
Manufacturer: Elsevier Science
Studio: Elsevier Science

Book Description:

Theoretical chemistry has been an area of tremendous expansion and development over the past decade; from an approach where we were able to treat only a few atoms quantum mechanically or make fairly crude molecular dynamics simulations, into a discipline with an accuracy and predictive power that has rendered it an essential complementary tool to experiment in basically all areas of science.


This volume gives a flavour of the types of problems in biochemistry that theoretical calculations can solve at present, and illustrates the tremendous predictive power these approaches possess.


A wide range of computational approaches, from classical MD and Monte Carlo methods, via semi-empirical and DFT approaches on isolated model systems, to Car-Parinello QM-MD and novel hybrid QM/MM studies are covered. The systems investigated also cover a broad range; from membrane-bound proteins to various types of enzymatic reactions as well as inhibitor studies, cofactor properties, solvent effects, transcription and radiation damage to DNA.


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شكرالك


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ISBN: 0824771168
Author: Koji Nakanishi
Publisher: Marcel Dekker
Publication Date: 1999-07-22
Number Of Pages: 512​

Book Description
A tribute to the pioneering scientific work of Professor Koji Nakanishi, whose studies of natural products have effaced some of the conventional boundaries between biology and chemistry. It discusses an array of chromatographic separation methods and determination of structures on a microscale, analyzes bioassay-directed fractionation and other means of isolating biologically active compounds from plants and other sources, covers vital enzymes isolated from marine organisms such as algae, and more​



Principles of Biochemical Toxicology


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Product Details
  • Paperback: 404 pages​
  • Publisher: Informa Healthcare; 3 edition (October 21, 1999)​
  • Language: English​
  • ISBN-10: 0748407367​
  • ISBN-13: 978-0748407361​
  • Product Dimensions: 9.6 x 7.1 x 0.8 inches​
Book Description
Research into the biochemical basis of toxicology has expanded rapidly over recent years, amidst concerns over the adverse effects of drugs, environmental pollution and occupational hazards. Following the acclaimed first two editions of Principles of Biochemical Toxicology, the author has expanded the text to include summary sections, questions and model answers and thoroughly revised artwork. These features, plus the new easy-to-read format, will make biochemical toxicology more accessible to undergraduates and postgraduates encountering the subject for the first time. This comprehensive textbook provides a thorough explanation of dose-response relationships, disposition and metabolism, toxic responses to foreign compounds and detailed examples to illustrate mechanisms of toxicity. Students and lecturers will find the clear and concise approach, which established this book as the leading textbook in its field, an essential aid to learning and teaching.





Biochemistry: The Molecular Basis of Life​


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Product Details
  • Hardcover: 800 pages​
  • Publisher: McGraw-Hill Science/Engineering/Math; 3 edition (July 23, 2002)​
  • Language: English​
  • ISBN-10: 007231592X​
  • ISBN-13: 978-0072315929​
  • Product Dimensions: 11.1 x 8.6 x 1.4 inches​
Product Description​

This textbook is intended for a diverse audience that ranges from chemistry majors to students in any of the life sciences. The logical organization (discussion of molecular structure immediately followed by the role it plays in metabolism) leads students through the complex world of biochemistry while an impressive art program helps to guide them through up-to-date concepts. Of special interest are the new Biochemical Methods boxes in the text, PowerPoint slides for instructors, and animated and annotated Chime structures of biomolecules in the OLC.​



Book Info


Univ. of the Sciences, Philadelphia, PA. Textbook provides an overview of the major physical and chemical techniques biochemists use to explore life at the molecular level. Features method boxes, coding information, and more than 700 new illustrations. Online learning site code is also included in textbook. Previous edition: c1999






An Introduction to Computational Biochemistry



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Product Details


  • Paperback: 368 pages​
Publisher: Wiley-Liss; 1st edition (April 30, 2002)
Language: English
ISBN-10: 047140120X
ISBN-13: 978-0471401209
Product Dimensions: 10 x 7.1 x 0.7 inches​


 


Enzymes, A Practical Introduction to Structure, Mechanism, and Data Analysis


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Publisher: Wiley-VCH

Number Of Pages: 397

Publication Date: 2000-03-15

ISBN-10 / ASIN: 0471359297

ISBN-13 / EAN: 9780471359296

Binding: Hardcover



Editorial Reviews

Review
"...a welcome volume for any reader concerned with this important class of biological.... The book is interesting, informative, and very readable." (Choice, Vol. 38, No. 7, March 2001)​


"...an introductory textbook intended for senior undergraduate or graduate students...coverage includes chemical bonds and reactions, structural components of enzymes..." (SciTech Book News, March 2001)
"...to describe this text in one word, I would say that it is thorougha good text for those interested in enzyme mechanisms and kinetics." (Journal of Medicinal Chemistry, Vol. 45, No. 235, 2002



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Springer Handbook of Enzymes Class 2 Transferases XI: EC 2.7.6 - 2.7.7


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Hardcover: 624 pages
Publisher: Springer; 2nd ed. edition (June 12, 2007)
Language: English
ISBN-10: 3540478078
ISBN-13: 978-3540478072
File type : PDF
File size : 19 MB


Book Description

The objective of the Springer Handbook of Enzymes is to provide in concise form data on enzymes sufficiently well characterized. Data sheets are arranged in their EC-Number sequence. The volumes are arranged according to enzyme classes. Considerable progress has been made in enzymology since the publication of the first edition (published as "Enzyme Handbook"): many enzymes are newly classified or reclassified. In the 2nd edition each entry is correlated with references and one or more source organisms. New datafields are created: "application" and "engineering" (for the properties of enzymes where the sequence has been changed). Altogether the amount of data has doubled so that the 2nd edition will consist of 39 volumes plus synonym index. This collection is an indispensable source of information for researchers in biochemistry, biotechnology, organic and analytical chemistry, and food sciences.


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بارك الله فيك

أشكرك على هذا جهد الجبار

Thank you very much

بارك الله فيك أخي جبار و جعله في ميزان حسناتك ...


شكرا لك اخي جبار ...دمت طيبا​

سعدت بمروركم جميعا احبائي بالاسرة الجميلة
لكم مني جميعا كل الحب والـتــــــقدير

وشـــــــــــكر خـــــــاص لمشرفنــــا الحبيب المهاجر سعدت جداً بحضورك الرائع معنا.. دائما

 


Medical Biochemistry


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  • Publisher: Mosby
    Number Of Pages: 696
    Publication Date: 2004-12-17
    ISBN-10 / ASIN: 0723433410
    ISBN-13 / EAN: 9780723433415​
  • Binding: Paperback​
Product Description
The New Edition of this well-regarded textbook combines basic science and clinical medicine in a concise, easy-to-read format. Fully revised and updated, it reflects the latest information on genetic and molecular biology and integrates even more clinical medicine into the text. At the same time, it retains the dynamic, full-color design that made the first edition such a successcomplete with case histories, advanced concept boxes, and color illustrations that clarify complex biochemical concepts. New summary boxes and an expanded self-assessment section make the text even more useful for review and study.

The smart way to study!
Elsevier titles STUDENT CONSULT will help you master difficult concepts and study more efficiently in print and online! Perform rapid searches. Integrate bonus content from other disciplines. Download text to your handheld device. And a lot more. Each STUDENT CONSULT title comes with full text online, a unique image library, case studies, USMLE style questions, and online note-taking to enhance your learning experience.​


  • Combines basic science and clinical practice in a concise and easy-to-read format.​
  • Organizes content by organ, rather than by body system.​
  • Uses a dynamic, full-color design, with case histories, advanced concept boxes, and clear photographs and illustrations​
 


Medical Biochemistry at a Glance



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Product Details


  • Paperback: 117 pages​
  • Publisher: Blackwell Publishing, Incorporated; 1st edition (January 15, 1996)​
  • Language: English​
  • ISBN-10: 0865429804​
  • ISBN-13: 978-0865429802​
  • Product Dimensions: 10.7 x 8.5 x 0.3 inches​
Book Info

St. Thomas's Hospital, London, U.K. Synopsis of biochemistry, to use as a supplement to major biochemistry texts, for medical students reviewing biochemistry. Emphasis on basic information and mechanisms. Includes detailed, explanatory diagrams and flow-charts. Softcover. DNLM: Biochemistry.

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