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Analytical and Practical Aspects of
Drug Testing in Hair
(Forensic Science)
By Pascal Kintz
Drug Testing in Hair
(Forensic Science)
By Pascal Kintz
Publisher: CRC
- Number Of Pages: 382
- Publication Date: 2006-08-30
- ISBN-10 / ASIN: 0849364507
- ISBN-13 / EAN: 9780849364501
- Binding: Hardcover
Product Description
Many advances have been made since the publication of Drug Testing in Hair. The mid-1990s witnessed the progress in cannabis detection while the late 1990s focused on benzodiazepines detection and the applications in doping control. In more recent years, toxicologists centered on the detection in hair of a single exposure and the related applications in drug-facilitated crimes. Presenting these topics as well as the latest findings from the international community, Analytical and Practical Aspects of Drug Testing in Hair reviews all new developments, the validation of analytical procedures, and the interpretation of data. Written by well-known, international authors, this comprehensive reference provides practical coverage of the best drug testing techniques and examines the drugs themselves. Some of the applications discussed include doping, drug-facilitated crime investigating, workplace testing, and the granting of drivers' licenses. The authors describe specific drugs, such as opiates, cocaine, and cannabis, and discuss the different testing methods for them. The book also covers postmortem toxicology, pitfalls created by passive exposure, and testing for metals, including inductively coupled plasma spectrometry (ICP-MS), hair multielementary analysis, and the new speciation analysis. A complete, up-to-date resource that explains numerous drug testing techniques, Analytical and Practical Aspects of Drug Testing in Hair provides useful information for toxicologists, forensic scientists, sports medicine specialists, and pathologists.
Contents
Drug Incorporation into Hair
- Hair Physiology
Drug Incorporation Routes
Mechanisms of Binding
Passive Exposure, Decontamination Procedures, Cutoffs, and Bias
Drugs in the Environment
Decontamination Procedures
Cutoffs and Why They Matter
Bias in Hair Testing
- Historical Concerns for Passive Exposure in Hair Analysis
Drugs in the Environment
Decontamination Procedures
Cutoffs and Why They Matter
Bias in Hair Testing
Opioids Testing in Hair
- Opiates
Hair Analysis for Cocaine
Interpretation of Results
- Analytical Methodologies
Interpretation of Results
Determination of Cannabinoids in Human Hair
Issues to Be Considered
Criteria for Obtaining a Cannabis-Positive Hair-Test Result
Controlled Studies: Empirical Data Analysis of a Large Sample of
Hair Specimens
Reported Concentrations of Cannabinoids in Hair
- Metabolism, Incorporation of Cannabinoids into Hair
Issues to Be Considered
Criteria for Obtaining a Cannabis-Positive Hair-Test Result
Controlled Studies: Empirical Data Analysis of a Large Sample of
Hair Specimens
Reported Concentrations of Cannabinoids in Hair
Amphetamine Determination in Hair
- Amphetamine Determination
Pharmaceuticals in Hair
Multianalyte Screening Using LC-MS/MS
Crime Cases Solved by Screening Hair Using LC-MS/MS
Screening Strategies in Hair Analysis on Drugs
- Immunochemical Screening in Hair Analysis
Multianalyte Screening Using LC-MS/MS
Crime Cases Solved by Screening Hair Using LC-MS/MS
Clinical Applications of Hair Analysis
Hair Analysis as Evidence of Prenatal and Postnatal Exposure to
Drugs and Tobacco
Hair Nicotine as a Marker of Active and Passive Exposure to Tobacco
Drug Addiction and Opiate-Maintenance Programs
Therapeutic Drug Monitoring
- Hair Analysis in Psychiatric Patients
Hair Analysis as Evidence of Prenatal and Postnatal Exposure to
Drugs and Tobacco
Hair Nicotine as a Marker of Active and Passive Exposure to Tobacco
Drug Addiction and Opiate-Maintenance Programs
Therapeutic Drug Monitoring
Hair in Postmortem Toxicology
- Methodological Aspects
Detection of Doping Agents in Human Hair
- Detection of Doping Agents
Applications of Hair in Drug-Facilitated Crime Evidence
- Analytical Strategy
Application of Hair in Driving-License Regranting
Hair Sampling for Drug Analysis
Manipulation of Drug Concentrations in Hair
Hair Analysis for Regranting Driver's License
Regulations in Other Countries
- Sensitivity of Drug Abuse Detection: Comparison between
Hair Sampling for Drug Analysis
Manipulation of Drug Concentrations in Hair
Hair Analysis for Regranting Driver's License
Regulations in Other Countries
Alcohol Markers in Hair
Ethylglucuronide (EtG)
Combined Use of FAEE and EtG
Benzoylecgonine Ethyl Ester (Cocaethylene, BE-Et)
- General Problems in Detection of Chronic Alcohol Abuse
Ethylglucuronide (EtG)
Combined Use of FAEE and EtG
Benzoylecgonine Ethyl Ester (Cocaethylene, BE-Et)
Workplace Drug Testing Using Hair Samples
Sample Preparation: Washing and Extraction Methods
Confirmation by Mass Spectrometry
Testing Body Hair Samples in Workplace Testing
- Sample Collection
Sample Preparation: Washing and Extraction Methods
Confirmation by Mass Spectrometry
Testing Body Hair Samples in Workplace Testing
Metals
Hair Elements Analytical Methods
Metal Hair Reference Values
Hair Metal Analysis Interpretation
Hair Metal Analysis Results
Metal Hair Certified Reference Material
- Hair Metal Incorporation
Hair Elements Analytical Methods
Metal Hair Reference Values
Hair Metal Analysis Interpretation
Hair Metal Analysis Results
Metal Hair Certified Reference Material
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