Michael F Moody, "Structural Biology Using Electrons and X-rays: An Introduction for Biologists"
Ac ademic Pr ess | 2011 | ISBN: 0123705819 | 450 pages | PDF | 5,2 MB
This book, suitable for advanced undergraduates or graduate students, provides an accessible introduction to the two major diffraction-based techniques of structural biology. While concentrating on electron cryo-microscopy with image analysis, it also includes X-ray crystallography in a coherent survey of fundamental principles. Starting with Fourier transforms and progressing through optics and imaging principles, symmetry and three-dimensional reconstruction theory, Structural Biology Using Electrons and X-rays ends in an account of the latest methods adapted to crystals, helices, viral heads, and single particles.
Key features:
-Emphasis on common principles underlying all diffraction-based methods
-Thorough grounding in theory requires understanding of only simple algebra
-Visual representations and explanations of challenging content
-Mathematical detail offered in short-course form to parallel the text
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