Organelle-Specific Pharmaceutical Nanotechnology
By Volkmar Weissig, Gerard G. D'Souza
By Volkmar Weissig, Gerard G. D'Souza
Wiley | ISBN: 0470631651 | 2010-11-02 | PDF | 622 pages | 9.40 Mb
This book introduces and discusses the latest in biomedical research--Pharmaceutical Nanotechnology applied at the sub-cellular level.
The subcellular, organelle-specific delivery of drugs has become the new frontier for drug delivery. Volkmar Weissig helped to initiate this development when, in 1998, he proposed a completely novel approach to delivering drugs to particular cell organelles, namely to mitochondria. A few years later, he was joined by Gerard D'Souza, and since then, they have been pioneering the field of mitochondria-specific drug delivery. Organelle-Specific Pharmaceutical Nanotechnology is their attempt to provide a clear overview of the state of the art in nanotechnology applied to subcellular drug delivery and probing the intercellular milieu in living cells.
This book brings together authors from several scientific disciplines to provide a broad view of the subject. Discussed in full detail are the various approaches to nanocarrier mediated bioactives to cell organelles, as well as emerging research methods for the identification of subcellular targeting ligands and the study of subcellular transport processes. All chapters have been written following a college course–like fashion, with a smooth transition from simple principles and methods to more complex material and research being conducted in the field.
Organelle-Specific Pharmaceutical Nanotechnology thus provides "need to know" information to every scientist interested in the development of new and effective nanotechnology-based therapeutic approaches. It will be of particular interest to scientists, postdoctoral investigators, and graduate students in the fields of drug delivery, subcellular transport phenomena, or the design of novel nanotechnological tools for biomedical applications.
