врач
Member
Many
times drugs work fine when tested outside the body, but when they are
tested in the body they fail. One of the major reasons a drug fails is
that it cannot be absorb by the body in a way to have the effect it was
intended to have. Permeability, Solubility, Dissolution, and Charged
State of Ionizable Molecules:
Helps drug discovery professionals to
eliminate poorly absorbable molecules early in the drug discovery
process, which can save drug companies millions of dollars.
Extensive tabulations, in appendix format, of properties and structures of about 200 standard drug molecules.
http://rapidshare.com/files/123750940/Abso_drg_dev.zip