السلام عليكم ورحمة الله وبركاته نرجو الحصول على الكتاب وجزاكم الله الخير Hardcover: 240 pages Publisher: CRC Press; 1 edition (29 Sep 2004) Language English ISBN-10: 084932050X ISBN-13: 978-0849320507 Product Dimensions: 23.4 x 15.2 x 1.8 cm Manel Esteller (Editor)
DNA Methylation: Approaches and Applications by Manel Esteller
DNA Methylation: Approaches and Applications by Manel Esteller Publisher: CRC (July 26, 2004) | 084932050X | PDF | 240Pages | 5.65MB
DNA Methylation: Approaches, Methods and Applications describes the relation DNA methylation has to gene silencing in disease, and explores its promising role in treating cancer. Written by leaders in the field, this exceptional compilation of articles outlines the best techniques to use when addressing questions concerning the cytosine methylation status of genomic DNA. It includes concepts, experimental models, and clinical uses of demethylating agents. The book provides a balance between articles clarifying methodological details and more general review chapters that offer broad biological perspectives on DNA methylation. This is an invaluable handbook for researchers and clinicians interested in genetics and molecular biology, particularly epigenetic therapies and gene silencing.
DNA Methylation: Methods and Protocols Publisher: Humana Press | Pages: 330 | 2008-11-28 | ISBN: 1934115614 | PDF | 6 MB
Product Description:
Over the past few years, DNA methylation technologies and our knowledge of DNA methylation patterns have been advancing at a breathtaking pace. Due to this fact, DNA Methylation: Methods and Protocols, Second Edition completely revises, updates, and expands upon the popular first edition with the most current novel techniques, easier to use and more refined by the tested experience of leading experts. This revision reflects contemporary study of the subject: the analysis of gene-specific DNA methylation patterns has been complemented by genome-wide approaches, and epigenomics takes a central place. Written in the highly successful Methods in Molecular Biology™ series format, the chapters in this volume present brief introductions to the topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes which highlight tips on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, DNA Methylation: Methods and Protocols, Second Edition is the perfect resource for scientists who wish to further our understanding of the molecular processes that determine the genomic DNA methylation landscape and for those who aim to identify and implement DNA methylation-based biomarkers for clinical and diagnostic applications.
