This well known textbook now appears in its 5th edition with an additional writer. The added colour has helped to produce a very readable book, with well laid out text and useful diagrams. It covers widely the curriculum needs of medical students as well as clinical scientists and other health care professionals. The use of case histories gives the book clinical relevance and the tables provide clear aide memoires for exam candidates. One criticism would be that I would like to have seen more detailed descriptions of how to investigate patients with biochemical problems.
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