Molecular Genetics Collection of Books

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An Introduction to Human Molecular Genetics​

Mechanisms of Inherited Diseases​

By Jack J. Pasternak​

Second Edition​


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  • Publisher: Wiley-Liss ​
  • Number Of Pages: 656 ​
  • Publication Date: 2005-06-03 ​
  • Binding: Hardcover ​
Product Description​




The Second Edition of this internationally acclaimed text expands its coverage of the molecular genetics of inherited human diseases with the latest research findings and discoveries. Using a unique, systems-based approach, the text offers readers a thorough explanation of the gene discovery process and how defective genes are linked to inherited disease states in major organ and tissue systems. All the latest developments in functional genomics, proteomics, and microarray technology have been thoroughly incorporated into the text.
The first part of the text introduces readers to the fundamentals of cytogenetics and Mendelian genetics. Next, techniques and strategies for gene manipulation, mapping, and isolation are examined. Readers will particularly appreciate the text's exceptionally thorough and clear explanation of genetic mapping. The final part features unique coverage of the molecular genetics of distinct biological systems, covering muscle, neurological, eye, cancer, and mitochondrial disorders. Throughout the text, helpful figures and diagrams illustrate and clarify complex material.
Readers familiar with the first edition will recognize the text's same lucid and engaging style, and will find a wealth of new and expanded material that brings them fully up to date with a current understanding of the field, including:
* New chapters on complex genetic disorders, genomic imprinting, and human population genetics
* Expanded and fully revised section on clinical genetics, covering diagnostic testing, molecular screening, and various treatments
This text is targeted at upper-level undergraduate students, graduate students, and medical students. It is also an excellent reference for researchers and physicians who need a clinically relevant reference for the molecular genetics of inherited human diseases.​




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Human Molecular Genetics​

Second Edition​

By Tom Strachan, Andrew P. Read



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  • Publisher: Wiley-Liss ​
  • Number Of Pages: 576 ​
  • Publication Date: 1999-12-15 ​
  • Binding: Paperback ​
Product Description



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Human Molecular Genetics 2 Tom Strachan & Andrew P. Read "truly a Rolls Royce amongst textbooks" — Molecular Medicine Today "the best text to introduce students and scientists to the molecular aspects of human genetics" — Trends in Genetics "a beautifully crafted book" — Journal of Medical Genetics "addresses the gap between introductory textbooks and the primary literature. There’s no other textbook quite like it." — Nature Now extensively rewritten and updated, HMG2 guides students and researchers through the very latest developments in the most rapidly changing area of life science. The highly regarded structure of the bestselling first edition is retained, but a wealth of new data and features have been added to aid understanding of the principles of human molecular genetics:
  • new material on cell types and the cell cycle, signal transduction, DNA mutation repair, and comparative genomics and evolution ​
  • new material on recent advances in the study of gene expression and function, including the use of DNA microarrays ​
  • the latest Genome Project data including an assessment of the impact of complete genome sequences and new approaches in functional genomics ​
  • expanded coverage of common disease susceptibility ​
  • new section on how best to obtain the latest data from web-based resources ​
  • a range of new figures, with many more in full color ​
  • the early use of hierarchical figures and flow charts to introduce principles described fully in later chapters ​
  • new two-column layout to improve clarity further ​
  • references systematically updated​
HMG2 is the book of choice for readers requiring an authoritative and integrated approach to human genetics.


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Primer on Molecular Genetics ​


by U.S. Department of Energy ​


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Contenent​

DOE Human Genome Program
Primer on Molecular Genetics
Date Published: June 1992
U.S. Department of Energy
Office of Energy Research
Office of Health and Environmental Research
Washington, DC 20585
The "Primer on Molecular Genetics" is taken from the June 1992 DOE Human
Genome 1991-92 Program Report. The primer is intended to be an introduction to
basic principles of molecular genetics pertaining to the genome project.
This is one the simpler explanation of all related topics in Human Genome project that can readily be understood even by a layman.
Contents
Primer on
Molecular
Genetics
Revised and expanded
by Denise Casey
(HGMIS) from the
primer contributed by
Charles Cantor and
Sylvia Spengler
(Lawrence Berkeley
Laboratory) and
published in the
Human Genome 1989–
90 Program Report.
Introduction ............................................................................................................. 5
DNA.............................................................................................................................. 6
Genes........................................................................................................................... 7
Chromosomes ............................................................................................................... 8
Mapping and Sequencing the Human Genome ...................................... 10
Mapping Strategies ..................................................................................................... 11
Genetic Linkage Maps ............................................................................................ 11
Physical Maps......................................................................................................... 13
Low-Resolution Physical Mapping...................................................................... 14
Chromosomal map ......................................................................................... 14
cDNA map ...................................................................................................... 14
High-Resolution Physical Mapping ..................................................................... 14
Macrorestriction maps: Top-down mapping ................................................... 16
Contig maps: Bottom-up mapping.................................................................. 17
Sequencing Technologies ........................................................................................... 18
Current Sequencing Technologies ......................................................................... 23
Sequencing Technologies Under Development ..................................................... 24
Partial Sequencing to Facilitate Mapping, Gene Identification ............................... 24
End Games: Completing Maps and Sequences; Finding Specific Genes .................. 25
Model Organism Research.............................................................................. 27
Informatics: Data Collection and Interpretation ..................................... 27
Collecting and Storing Data ........................................................................................ 27
Interpreting Data ......................................................................................................... 28
Mapping Databases .................................................................................................... 29
Sequence Databases .................................................................................................. 29
Nucleic Acids (DNA and RNA)................................................................................ 29
Proteins .................................................................................................................. 30
Impact of the Human Genome Project ​

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Molecular and Genetic Analysis of Human Traits​

By Gustavo Maroni​



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  • Publisher: Wiley-Blackwell
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  • Number Of Pages: 274 ​
  • Publication Date: 2001-01-15 ​
  • Binding: Paperback ​
Product Description





Molecular and Genetic Analysis of Human Traits will address the science student human genetics market. Although incorporating two basic themes: how do we establish that a trait is hereditary, and how is the human genome organized, it will also address relevant clinical examples and key related ethical issues. New attractive features have been added, including a chapter project, and end of chapter exercises which rely on real data.
Each chapter includes end of chapter exercises, and references. ​

  • In-text examples and internet references are cited.
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  • Most figures will be 2 color, with some 4 color inserts.​
 
Molecular Genetics and the Human Personality

By Jonathan Benjamin, Richard P. Ebstein, Robert H. Belmaker

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  • Publisher: American Psychiatric Publishing, Inc. ​
  • Number Of Pages: 378 ​
  • Publication Date: 2002-03 ​
  • Binding: Hardcover ​

Product Description

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Ben Gurion Univ. of the Negev, Beersheva, Israel. Explores the new era of study made possible by the pace of discovery and innovation in the field of molecular genetics. Reflects the point of view of the 35 contributors. For students and others interested in evaluating and exploring the relationship between molecular genetics and the human personality. DNLM: Personality Disorders.

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From Molecular Genetics to Genomics

The Mapping Cultures of Twentieth Century Genetics ​

(Studies in the History of Science, Technology and Medicine)​



By J. Gaudilliere​





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  • Publisher: Routledge
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  • Number Of Pages: 336 ​
  • Publication Date: 2004-11-23 ​
  • Binding: Hardcover ​
Product Description
With the rise of genomics, the life sciences have entered a new era. This book provides a comprehensive history of molecular genetics and genomics.​


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cairou university
 
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