Protein-Protein Interactions as New Drug Targets

chemistry

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Protein-Protein Interactions as New Drug Targets
Handbook of Experimental Pharmacology
by
Enno Klussmann, John Scott
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By
Publisher: Springer
Number Of Pages: 512
Publication Date: 2008-08-06
ISBN-10 / ASIN: 3540728422
ISBN-13 / EAN: 9783540728429
Binding: Hardcover

BooK Description
Disease-relevant intracellular protein-protein interactions occurring at defined cellular sites possess great potential as drug targets. They permit highly specific pharmacological interference with defined cellular functions.Drugs targeting such interactions are likely to act with fewer side effects than conventional medication influencing whole cell functions.
This book discusses therapeutically relevant protein-protein interactions with a major focus on scaffolding proteins tethering signal transduction processes to defined cellular compartments by direct protein-protein interactions. Recent advances in the development of pharmacological agents interfering with protein-protein interactions are highlighted

 


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