Free Energy Calculations in Rational Drug Design

صيدلانية سعودية

مشرفة قسم الصيدلة
Free Energy Calculations in Rational Drug Design
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Product Details

Hardcover: 406 pages
Publisher: Springer; 1 edition (October 1, 2001)
Language: English
ISBN-10: 0306466767
ISBN-13: 978-0306466762

Editorial Reviews

Review
`Free Energy Calculations in Rational Drug Design is an impressive volume. It should be a good reference for those interested in applications.The book should be included in any academic or industrial library. Its cost is easily justified.'
Journal of Medicinal Chemistry, 46:11 (2003)

Product Description
Free energy calculations represent the most accurate computational method available for predicting enzyme inhibitor binding affinities. Advances in computer power in the 1990s enabled the practical application of these calculations in rationale drug design. This book represents the first comprehensive review of this growing area of research and covers the basic theory underlying the method, numerous state of the art strategies designed to improve throughput and dozen examples wherein free energy calculations were used to design and evaluate potential drug candidates
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