Acid-Base Chemistry

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Water

We typically talk about acid-base reactions in aqueous-phase environments -- that is, in the presence of water. The most fundamental acid-base reaction is the dissociation of water:

h20.gif

In this reaction, water breaks apart to form a hydrogen ion (H+) and a hydroxyl ion (OH-). In pure water, we can define a special equilibrium constant (Kw) as follows:
kw.gif

Where Kw is the equilibrium constant for water (unitless)
[H+] is the molar concentration of hydrogen
[OH- is the molar concentration of hydroxide

An equilibrium constant less than one (1) suggests that the reaction prefers to stay on the side of the reactants -- in this case, water likes to stay as water. Because water hardly ionizes, it is a very poor conductor of electricity.
pH

What is of interest in this reading, however, is the acid-base nature of a substance like water. Water actually behaves both like an acid and a base. The acidity or basicity of a substance is defined most typically by the pH value, defined as below:

ph.gif

At equilibrium, the concentration of H+ is 10-7, so we can calculate the pH of water at equilibrium as:
pH = -log[H+]= -log[10-7] = 7
Solutions with a pH of seven (7) are said to be neutral, while those with pH values below seven (7) are defined as acidic and those above pH of seven (7) as being basic.
pOH gives us another way to measure the acidity of a solution. It is just the opposite of pH. A high pOH means the solution is acidic while a low pOH means the solution is basic.
pOH = -log[OH-]
pH + pOH = 14.00
Definitions of acids and bases
  • Arrhenius
    acid: generates [H+] in solution
    base: generates [OH-] in solution
    normal Arrhenius equation: acid + base <---> salt + water
    example: HCl + NaOH <---> NaCl + H2O
  • Bronsted-Lowery:
    acid: anything that donates a [H+] (proton donor)
    base: anything that accepts a [H+] (proton acceptor)
    normal Bronsted-Lowery equation: acid + base <---> acid + base
    example: HNO2 + H2O <---> NO2- + H3O+
    Each acid has a conjugate base and each base has a conjugate acid. These conjugate pairs only differ by a proton. In this example: HNO2 is the acid, H2O is the base, NO2- is the conj. base, and H3O+ is the conj. acid.
  • Lewis:
    acid: accepts an electron pair
    base: donates an electron pair
    The advantage of this theory is that many more reactions can be considered acid-base reactions because they do not have to occur in solution.
Salts

A salt is formed when an acid and a base are mixed and the acid releases H+ ions while the base releases OH- ions. This process is called hydrolysis. The pH of the salt depends on the strengths of the original acids and bases:

AcidBaseSalt pHstrongstrongpH = 7weakstrongpH > 7strongweakpH < 7weakweakdepends on which is stronger
This is because the conjugate base of a strong acid is very weak and cannot undergo hydrolysis. Similarly, the conjugate acid of a strong base is very weak and likewise does not undergo hydrolysis. Acid-Base Character

For a molecule with a H-X bond to be an acid, the hydrogen must have a positive <A href="http://www.shodor.org/UNChem/glossary.html#oxidationnumber">oxidation number so it can ionize to form a positive +1 ion. For instance, in sodium hydride (NaH) the hydrogen has a -1 charge so it is not an acid but it is actually a base. Molecules like CH4 with nonpolar bonds also cannot be acids because the H does not ionize. Molecules with strong bonds (large electronegativity differences), are less likely to be strong acids because they do not ionize very well. For a molecule with an X-O-H bond (also called an oxyacid) to be an acid, the hydrogen must again ionize to form H+. To be a base, the O-H must break off to form the hydroxide ion (OH-). Both of these happen when dealing with oxyacids.

Strong Acids: These acids completely ionize in solution so they are always represented in chemical equations in their ionized form. There are only seven (7) strong acids:
HCl, HBr, HI, H2SO4, HNO3, HClO3, HClO4
To calculate a pH value, it is easiest to follow the standard "Start, Change, Equilibrium" process.
Example Problem: Determine the pH of a 0.25 M solution of HBr.
prob6.gif

Weak Acids: These are the most common type of acids. They follow the equation:
HA(aq) <---> H+(aq) + A-(aq)
The equilibrium constant for the dissociation of an acid is known as Ka. The larger the value of Ka, the stronger the acid.
ka.gif

Example Problem: Determine the pH of .30 M acetic acid (HC2H3O2) with the Ka of 1.8x10-5.
prob1.gif

Strong Bases: Like strong acids, these bases completely ionize in solution and are always represented in their ionized form in chemical equations. There are only eight (8) strong bases:
LiOH, NaOH, KOH, RbOH, CsOH, Ca(OH)2, Sr(OH)2, Ba(OH)2
Example Problem: Determine the pH of a 0.010 M solution of Ba(OH)2.
prob7.gif

Weak Bases: They follow the equation:
Weak Base + H2O <---> conjugate acid + OH-
example: NH3 + H2O <---> NH4+ + OH+
Kb is the base-dissociation constant:
kb.gif

Ka x Kb = Kw = 1.00x10-14
To calculate the pH of a weak base, we must follow a very similar "Start, Change, Equilibrium" process as we did with the weak acid, however we must add a few steps.
Example Problem: Determine the pH of 0.15 M ammonia (NH3) with a Kb=1.8x10-5.
prob2.gif

When dealing with weak acids and weak bases, you also might have to deal with the "common ion effect". This is when you add a salt to a weak acid or base that contains one of the ions present in the acid or base. To be able to use the same process to solve for pH when this occurs, all you need to change are your "start" numbers. Add the molarity of the ion, which comes from the salt, and then solve the Ka or Kb equation as you did earlier.
Example Problem: Find the pH of a solution formed by dissolving 0.100 mol of HC2H3O2 with a Ka of 1.8x10-8 and 0.200 mol of NaC2H3O2 in a total volume of 1.00 L.
prob8.gif

Acid-Base Titrations

An acid-base <A href="http://www.shodor.org/UNChem/glossary.html#titration">titration is when you add a base to an acid until the equivalence point is reached which is where the moles of acid equals the moles of base. For the titration of a strong base and a strong acid, this equivalence point is reached when the pH of the solution is seven (7) as seen on the following titration curve:

ex1.gif

For the titration of a strong base with a weak acid, the equivalence point is reached when the pH is greater than seven (7). The half equivalence point is when half of the total amount of base needed to neutralize the acid has been added. It is at this point where the pH = pKa of the weak acid.
ex2.gif

In an acid-base titration, the base will react with the weak acid and form a solution that contains the weak acid and its conjugate base until the acid is completely gone. To solve these types of problems, we will use the weak acid's Ka value and the molarities in a similar way as we have before. Before demonstrating this way, let us first examine a short cut, called the Henderson-Hasselbalch Equation. This can only be used when you have some acid and some conjugate base in your solution. If you only have acid, then you must do a pure Ka problem and if you only have base (like when the titration is complete) then you must do a Kb problem.
hhas.gif

Where:
pH is the log of the molar concentration of the hydrogen
pKa is the equilibrium dissociation constant for an acid
[base] is the molar concentration of a basic solution
[acid] is the molar concentration of an acidic solution

Example Problem: 25.0 mL of .400 M KOH is added to 100. mL of .150 M benzoic acid, HC7H5O2 (Ka=6.3x10-5). Determine the pH of the solution.
prob3.gif

This equation is used frequently when trying to find the pH of buffer solutions. A buffer solution is one that resists changes in pH upon the addition of small amounts of an acid or a base. They are made up of a conjugate acid-base pair such as HC2H3O2/C2H3O2- or NH4+/NH3. They work because the acidic species neutralize the OH- ions while the basic species neutralize the H+ ions. The buffer capacity is the amount of acid or base the buffer can neutralize before the pH begins to change to an appropriate degree. This depends on the amount of acid or base in the buffer. High buffering capacities come from solutions with high concentrations of the acid and the base and where these concentrations are similar in value.
Practice weak acid problem:
C6H5COONa is a salt of a weak acid C6H5COOH. A .10 M solution of C6H5COONa has a pH of 8.60.
  1. calculate [OH-] of C6H5COONa
  2. calculate K for: C6H5COO- + H2O <---> C6H5COOH + OH-
  3. calculate Ka for C6H5COOH
See the weak acid solution.
Practice titration problem:
20.00 mL of 0.160 M HC2H3O2 (Ka=1.8x10-5) is titrated with .200 M NaOH.
  1. What is the pH of the solution before the titration begins?
  2. What is the pH after 8.00 mL of NaOH has been added?
  3. What is the pH at the equivalence point?
  4. What is the pH after 20.00 mL of NaOH has been added?
 
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