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"Systems Biology in Drug Discovery and Development
(Wiley Series on Technologies for the Pharmaceutical Industry)
Publisher:
ISBN: 047_0261234 |
2011
PDF
380 pages
10.4 MB
This is the first comprehensive systems biology book to focus on its applications in drug discovery and development. Using real-world examples, the book shows how systems biology can be used to enhance pharmaceutical research and drug development. It highlights essential components of drug discovery like target identification and validation and complementary systems approaches like text-mining, large multi-context datasets and regression modeling. It also provides models for treatment personalization and methods for applying systems biology to pharmacokinetics, pharmacodynamics, and candidate biomarker indentification. Introducing key methods and technical approaches the book addresses the challe
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