كيمياء حيوية سلسلة من كتب عن الكيمياء الحيوية

The Biochemistry of Cell Signalling

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• Publisher: Oxford University Press, USA
  Number Of Pages: 368
  Publication Date: 2001-09-13
  ISBN-10 / ASIN: 0198508204
  ISBN-13 / EAN: 9780198508205 ​
• Binding: Paperback ​

The Biochemistry of Cell Signalling deals in depth with the principles of cell signalling, concentrating on structure and mechanism. It will serve as a reliable map through the maze of cell signalling pathways and help the reader understand how malfunctions in these pathways can lead to disease. The book is divided into four parts. Part 1 describes the machinery of signal transduction starting with the properties of signals, receptors (including receptor activation), regulators, and the molecules that link receptor and regulator. The design of signalling cascades is explained by describing central signalling pathways: the Ras-regulated MAPK and PI-3 pathways; the Rho/Rac/Cdc 42 pathway controlling chemotaxis and regulating the cytoskeleton; the G protein coupled receptor cascades in response to sensory and hormonal signals; signalling by TGF-ss in morphogenesis; cytokine signalling that controls haemopoiesis. There is also a discussion of the insulin response. As phosphorylation - dephosphorylation is involved in nearly all cellular regulatory processes, Part 1 concludes with a synopsis of its role in signalling. Part 2 describes the implementation of the signalling cascades focusing on the effect on gene transcription. After a brief description of the transcriptional machinery the regulation of transcription by cytokines and growth factors in the control of cell growth and the mechanisms and sites of control are discussed in detail. The regulators discussed include Jun/Fos, NF-AT, SREBPs, and STATs. The next two chapters cover gene regulation by nuclear receptors, including both the steroid hormone receptors and non-steroid nuclear receptors e.g. the retinoic acid receptors RAR and RXR. Part 3 studies the global cellular regulatory programs for the control of cell growth and proliferation. The first chapter concerns the regulation of the cell cycle and the role of the cyclin-dependent kinases, telomerase, Ran, and cell cycle checkpoints. The next topic is the signalling pathways in apoptosis: the TNF-receptor family death receptors, caspases, and the intracellular apoptosis signals and the role of apoptosis in the lifecycle of cells. Part 3 ends with a discussion of the signal pathways involved in the immune response, focusing on the involvement of cell-cell interactions. Part 4 considers loss of regulatory control and its consequences with respect to the molecular basis of cancer. It first describes the cellular regulatory proteins that have oncogenic potential, how they can become oncogenic and cause the transformation of normal cells to cancerous cells. Next is an analysis of the loss of developmental controls, the APC protein, ss-catenin, and the Wnt pathway, that lead to mature terminally differentiated cells reverting to immature embryonic cells. The book ends with a summary of the molecular and cellular causes of cancer and an outlook for novel therapies. Throughout the text, the emphasis is on structure and mechanism and is well illustrated with 200 figures. The Biochemistry of Cell Signalling will be an invaluable companion to all graduate students studying cell signalling.


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THANK YOU very Much

 

بارك الله فيك اخي العزيز جبار دائما سباق الى الخير

 

Publisher: John Wiley & Sons
Number Of Pages: 292
Publication Date: 1994-07
ISBN-10 / ASIN: 3527282696
ISBN-13 / EAN: 9783527282692
Binding: Paperback


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Color Atlas of Biochemistry, 2nd edition, revised and enlarged




Product Details​

• Paperback: 467 pages​
• Publisher: Thieme Medical Publishers; 2 Rev Enl edition (December 2004)​
• Language: English​
• ISBN-10: 1588902471​
• ISBN-13: 978-1588902474​
• Product Dimensions: 7.5 x 5.1 x 1 inches​

Book Description
Basic biochemistry in color pictures! This book focuses on particular and fundamental aspects of human and mammalian biochemistry. Besides coverage of structure and composition of biologically relevant molecules and their metabolism, it also includes interlinking of chemical structures with biological functions, how molecules are arranged in cellular space and in the organism, and the evolution of biochemical processes.

Language Notes
Text: English (translation)
Original Language: German --This text refers to an out of print or unavailable edition of this title

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Product Details​

• Hardcover: 320 pages​
• Publisher: Wiley-VCH; Har/Cdr edition (May 23, 2008​
• Language: English​
• ISBN-10: 3527319573​
• ISBN-13: 978-3527319572​
• Product Dimensions: 9.4 x 6.7 x 0.9 inches​

Product Description
This new, expanded and updated edition of the user-friendly and comprehensive treatise on enzyme kinetics expertly balances theory and practice. With its easy-to-use program on CD-ROM containing examples allowing for the interpretation of experimental data, this is an indispensable aid for advanced students and professionals working with enzymes, whether biochemists, biotechnologists, chemical biologists, pharmacologists or bioengineers in academia, industry and clinical research.

About the Author
Prof. Dr. Hans Bisswanger is currently at the Interfaculty Institute of Biochemistry at the University of T?n. He has developed and leads an intensive course on enzyme kinetics, enzyme technology and ligand binding, while his main focus is on structural and regulatory mechanisms of multi-enzyme complexes and temperature stable enzyme complexes. He is also working on the gentle immobilization of enzyme activities on synthetic surfaces, a method which has been favorably applied for the restoration of damaged documents



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Phenolic Compound Biochemistry




Academic Press | ISBN: 0120954400 | 4th edition (July, 2001) | 1060 pages | PDF | 88 MB

Product Description

How does the consumption of red wine reduce heart disease? How does a plant battle an invading fungus using physical and chemical defense mechanisms? How are tannins used in leather production synthesized?
These are just a few examples that illustrate the chemical diversity and use of phenolic compounds, the topic of Phenolic Compound Biochemistry.
This book is written for researchers, instructors, advanced undergraduate students and beginning graduate students in the life sciences who wish to become more familiar with these and many other intriguing aspects of phenolic compounds. Topics covered include nomenclature, chemical properties, biosynthesis, including an up-to-date overview of the genetics controlling phenolic metabolism, isolation and characterization of phenolic compounds, phenolics used in plant defense, and the impact of phenolics on human health. The book is written in an accessible style, and assumes only basic knowledge of organic chemistry, biochemistry and cell physiology. More than 300 chemical structures and reaction schemes illustrate the text.
Wilfred Vermerris is Associate Professor of Agronomy at the University of Florida Genetics Institute in Gainesville, FL. His research focuses on the genetic control of phenolic compounds that impact agro-industrial processing of crop plants.
Ralph Nicholson is Professor of Botany and Plant Pathology at Purdue University in West Lafayette, IN. He is an expert on phenolic compounds involved in the plants defense against pathogenic fungi and bacteria

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A Manual for Biochemistry Protocols





By Markus R. Wenk, Aaron Z. Fernandis,​

• Publisher: World Scientific Publishing Company ​
• Number Of Pages: 140 ​
• Publication Date: 2007-03-30 ​
• Sales Rank: 2535599 ​
• ISBN / ASIN: 9812700668 ​
• EAN: 9789812700667 ​
• Binding: Spiral-bound ​
• Manufacturer: World Scientific Publishing Company ​
• Studio: World Scientific Publishing Company ​
• Average Rating: ​
• Total Reviews: ​

Product Description:
Biochemistry plays an important role in all areas of the biological and medical sciences. With most of the research or diagnosis involved in these areas being based on biochemically obtained observations, it is essential to have a profile of well standardized protocols. This manual is a basic guide for all students, researchers and experts in biochemistry, designed to help readers in directly starting off their experiments without prior knowledge of the protocol. The book dwells on the concepts used in designing the methodologies, thereby giving ample room for researchers to modify them according to their research requirements.



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بارك الله فيك اخي جبار

 

Cyclodextrins and Their Complexes: Chemistry, Analytical Methods, Applications





Product Details:

Hardcover: 507 pages
Publisher: John Wiley & Sons (August 30, 2006)
Language: English
ISBN: 3527312803


Book Description:

Offering comprehensive and up-to-date know-how in one compact book, an experienced editor and top authors cover every aspect of these important molecules from molecular recognition to cyclodextrins as enzyme models.

Chapters include reactivity and chemistry, chromatography, X-ray, NMR plus other physicochemical methods, as well as model calculations, rotaxane and catenane structures, and applications in the pharmaceutical industry. The book also discusses other applications such as in the cosmetics, toiletries, textile and wrapping industries, agrochemistry, electrochemical sensors, and devices.

A must for everyone working with these substances.

From the Back Cover
Offering comprehensive and up-to-date know-how in one compact book, an experienced editor and top authors cover every aspect of these important molecules from molecular recognition to cyclodextrins as enzyme models.
Chapters include reactivity and chemistry, chromatography, X-ray, NMR plus other physicochemical methods, as well as model calculations, rotaxane and catenane structures, and applications in the pharmaceutical industry. The book also discusses other applications such as in the cosmetics, toiletries, textile and wrapping industries, agrochemistry, electrochemical sensors, and devices.
A must for everyone working with these substances





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Chemical Biology: From Small Molecules to Systems Biology and Drug Design(3-Volume Set)


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• Publisher: Wiley-VCH ​
• Number Of Pages: 1280 ​
• Publication Date: 2007-04-20 ​
• ISBN-10 / ASIN: 3527311505 ​
• ISBN-13 / EAN: 9783527311507 ​
• Binding: Hardcover ​

Product Description:

Edited by the world leaders in this emerging field, this three-volume handbook is designed to become the landmark reference on this exciting new branch of chemistry and biology.
Following an introductory section, the authors discuss the use of small molecules to explore biology, discovering small molecule probes for biological mechanisms and expanding the scope of chemical synthesis. Further sections cover chemical informatics, drug discovery and systems biology, and the whole work is rounded off by the outlook and perspectives for this field.
No academic institution or pharmaceutical company can possibly miss out on this highly authoritative work


part1:

part2: ​

 

بارك الله فيك و جعله الله فى ميزان حسناتك

 

Biomaterials

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• Publisher: CRC ​
• Number Of Pages: 296 ​
• Publication Date: 2007-06-07 ​
• ISBN-10 / ASIN: 0849378885 ​
• ISBN-13 / EAN: 9780849378881 ​
• Binding: Hardcover ​

Product Description:


For medical devices that must be placed inside the body, the right choice of material is the most important aspect of design. To ensure such devices are safe, reliable, economical, and biologically and physiologically compatible, the modern biomedical engineer must have a broad knowledge of currently available materials and the properties that affect their in-service performance. In chapters drawn from the third edition of the best-selling Biomedical Engineering Handbook, Biomaterials surveys the wide variety of biomaterials in present use as well as materials resulting from novel micro- and nanoscale technologies. ​

The book includes a general overview of bioinert, bioactive or surface reactive ceramics, and biodegradable or re-absorbable bioceramics. It reviews basic chemical and physical properties of the synthetic polymers, covers the sterilization of the polymeric biomaterials, discusses the importance of the surface treatment for improving biocompatibility, and examinesthe application of the chemogradient surface for the study on cell polymer interactions. The book also provides an overview of the chemistry design, fabrication, and application of biodegradable hydrogels for drug delivery and tissue engineering. It explores current issues involved in probing cell-biomaterials interactions on the molecular level and their implications for tissue engineering research and examines advances in biodegradable polymeric materials, soft and hard tissue replacements, and applications in tissue engineering.

Taking a focuses look at the latest advances in biomaterials, the book discusses metallic, ceramic, polymeric, and composite biomaterials. With more than 100 figures and tables, as well as contributions from a panel of international experts, the book gives you familiarity with the uses of biomaterials in medicine and dentistry.


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Amino Group Chemistry: From Synthesis to the Life Sciences

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• Publisher: Wiley-VCH ​
• Number Of Pages: 408 ​
• Publication Date: 2008-01-28 ​
• ISBN-10 / ASIN: 3527317414 ​
• ISBN-13 / EAN: 9783527317417 ​
• Binding: Hardcover ​

Product Description:

Here, probably the most important functional group in organic chemistry is discussed in one handy volume. The monograph covers its application -- from natural products to synthetic pharmaceuticals -- detailing complex syntheses using the amino group as templates and modern techniques focussing on the introduction of the amino group. A definitive must-have for every chemist.


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Molecular Modeling of Proteins (Methods in Molecular Biology)


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• Publisher: Humana Press ​
• Number Of Pages: 396 ​
• Publication Date: 2008-02-19 ​
• ISBN-10 / ASIN: 1588298647 ​
• ISBN-13 / EAN: 9781588298645 ​
• Binding: Hardcover ​

Product Description:


Molecular modeling has undergone a remarkable transformation in the last 20 years, as biomolecular simulation moves from the realm of specialists to the wider academic community. Molecular Modeling of Proteins provides thorough introductions and a compilation of step-by-step methods applicable to problems faced by non-specialists – especially those new to the software packages used in molecular modeling. Tips on troubleshooting and avoiding common pitfalls are included in this book, along with chapters covering a wide range of subjects ranging from free energy calculation to applications for drug design. Written by an internationally distinguished panel of investigators and outlining the most striking developments in the field, Molecular Modeling of Proteins is an invaluable resource for those in the industry, as well as a cutting-edge reference for students and professionals in the fields of chemistry, biochemistry, biology, biophysics and bioinformatics.


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